Companies founded by OpenAI alumni

Thinking Machines Lab develops tools and models that make advanced AI systems more customizable and capable. Its work includes Tinker, an API for training and fine-tuning models, and Inkling, an open-weight model designed for efficient experimentation.

Anthropic develops the Claude family of AI systems and conducts research on interpretability, alignment, model behavior, and safer scaling. Its work includes Constitutional AI and a Responsible Scaling Policy intended to connect stronger capabilities with corresponding safeguards.

Periodic Labs is building AI scientists that can propose ideas, run experiments in autonomous laboratories, and learn from the results. Starting with materials science, it aims to generate the experimental data needed to discover materials such as higher-temperature superconductors rather than relying only on published research.

AI safety-focused research company founded by Ilya Sutskever, Daniel Gross, and Daniel Levy. Focused exclusively on building safe superintelligence, with no products or near-term commercial pressure.

AI search company building answer engines that combine web retrieval, citations, and conversational interfaces.

AI startup building enterprise-specific agents and infrastructure for training, deploying, and continuously improving models on company workflows and data. In April 2026 it announced an $80 million round led by Kleiner Perkins, bringing total funding to $160 million.

Adept builds multimodal agents that understand screens and carry out multi-step work across business software. Its ACT-1 model was an early attempt to turn natural-language instructions into clicks, typing, and other computer actions. In 2024, Amazon hired Adept's co-founders and part of its team and licensed its models, data, and agent technology; Adept continued under new leadership with an enterprise-agent focus.

Robotics AI company developing foundation models and robot-learning systems for warehouse automation and industrial manipulation.

Contact-center AI company founded by Zayd Enam, Tim Shi, and Sebastian Thrun out of the Stanford AI Lab. Builds a generative-AI platform that coaches and assists customer-service agents in real time.